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Genomics
Written primarily for 16-19 year old students, this primer aims to extend students' knowledge and inspire them to take their school-level learning further.It explores topics that are familiar from the curriculum and also introduces new ideas, giving students a first taste of the study of biology beyond school-level and demonstrating how concepts frequently encountered at school are relevant to and applied in current research.This is the ideal text to support students who are considering making the transition from studying biology at school to university. This Oxford Biology Primer will introduce students to the field of genomics and its applications.From the early days of the Human Genome Project, sequencing technology has rapidly developed and is now cheaper and more accessible than ever before.The resulting pervasive nature of these technologies make them more likely to be experienced by people as patients, consumers and citizens. The primer introduces the basic principles of genomics and then uses these to consider human genetics, through examples of some of the rare diseases linked to single genes.The impact of these rare diseases is far-reaching and the knowledge gained through genome sequencing is proving invaluable in their diagnosis.Genome sequencing is revolutionising the diagnosis and treatment of cancer, and the primer introduces students to some of the key breakthroughs which have taken place in recent years.These include the identification of specific genes indicating cancer risk, and the sequencing of tumours throughout treatment to identify further mutations and modify treatment accordingly. The primer aims to address a number of the ethical issues which are raised by this rapidly-growing area of biology.Students are challenged to consider some of the decisions they may need to make relating to these technologies in their own lives, and are given opportunities to explore different aspects of these issues in a way which allows discussion to be both informed and meaningful. The study of infectious disease is also feeling the impact of genomics: the primer discusses the concept of pathogen genome sequencing, and illustrates the various ways in which this can be used - for example, enabling us to find different solutions to infections, to track outbreaks of disease to their source, and to identify and possibly ultimately combat antibiotic resistance. Many of the major diseases which impact the global population are caused by parasites, which come in a wide variety of shapes and sizes.The primer introduces students to the importance of understanding parasite genomes.Parasite genome sequencing makes it possible to develop both new medicines, and new treatments such as gene drive systems to wipe out disease-causing mosquito populations. For many years, our views of classification and evolution have been based on observational techniques going back to Darwin and Linnaeus.Focusing on human evolution, the primer will open students' eyes to the ways in which genome sequencing is being used to reveal evolutionary links that have never before been recognised, and to elucidate the way humans spread out of Africa across the world.Students are not always aware of the role technological developments play in enabling the progress of science.The final chapter delves into how genome sequencing technologies have developed, considering both the speed of change in the technology, its implications for usefulness, availability and cost, and the growing issue of big data and how it can be manipulated.The different technologies described in this chapter are referenced throughout the book.
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Plant Genomics
Introduction to the range of molecular techniques to investigate unique facets of plant growth, development, and responses to the environment Plant Genomics introduces the complex relationship between the genome, microbiome, genes, and epigenetics of plants, as well as the range of molecular techniques applicable to investigating the unique facets of plant growth, development, and response to the environment.State-of-the-art science in the field is discussed, as well as future outlooks on what the next decade is likely to bring.This book includes new techniques for modifying the plant genome and their impact on modifying plants to combat the impact of biotic and abiotic stresses, including those associated with climate change, new technologies including long and short read sequencing and proximity ligation and the combination of these technologies for assembling sequence data into chromosomes, a new chapter on the sequences of the chloroplast and mitochondrial genomes, and a dedicated chapter to epigenetics and the importance in gene regulation.Written by a highly qualified author with significant published research contributions to the field, Plant Genomics includes information on: Structure and information content of the chloroplast and mitochondrial genomes and their use in phylogenyUse of transcriptomes from various tissues to identify expressed sequences and their identification as genesFunction of small regulatory RNAs and long non-coding RNAs and involvement of small RNAs in the control of gene expressionEpigenetic silencing of transposable elements and their release by stress and cross-generational contribution of epigenetic variationUse of the pan-genome to assemble a comprehensive germplasm for a particular crop species Plant Genomics is an ideal textbook for undergraduate courses on plant biology, particularly those focusing on molecular descriptions, and a helpful auxiliary text to plant biology laboratory courses.It will also be of interest to students in plant molecular biology, agricultural and food sciences, and plant, food, and crop bioengineering.
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Introduction to Genomics
Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism.Yet it is more than a static information store: our genome is a dynamic, tightly regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed.But how do we identify the genes that make up our genome?How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life?Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time.Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes.The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. Digital formats and resourcesThe book is available for students and institutions to purchase in a variety of formats, and is supported by online resources:· The e-book offers a mobile-compatible experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks· Online resources, available for registered adopters, include downloadable figures and tables from the book· E-book and Trove formats are enriched with online resources for students, including extensive and imaginative weblems (web-based problems) for each chapter; hints and answers to end-of-chapter problems and exercises to support self-directed learning; a guided tour of websites and major archival databanks in genomics to springboard further research; Journal Club (links to related research articles on topics covered in the book paired with engaging questions); and rotating figures which allow readers to visualize complex structures.
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Introduction to Genomics
Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism.Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed.But how do we identify the genes that make up our genome?How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life?Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time.Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes.The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing.The Online Resource Centre accompanying Introduction to Genomics features: For students: - Extensive and imaginative weblems (web-based problems) for each chapter designed to give you practice with the tools required for further study and research in the field- Hints and answers to end-of-chapter problems and exercises support your self-directed learning- Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research - Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primary literature- Rotating figures allow you to visualize complex structuresFor registered adopters: - Downloadable figures from the book.
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Which hobbies involve being outdoors in nature?
Hobbies that involve being outdoors in nature include hiking, birdwatching, gardening, camping, fishing, and photography. These activities allow individuals to connect with the natural world, breathe in fresh air, and enjoy the beauty of the outdoors. Engaging in these hobbies can also provide physical and mental health benefits, such as reducing stress and increasing physical activity.
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In which profession do people conduct research outdoors in nature?
People who work as field biologists, ecologists, environmental scientists, geologists, or botanists often conduct research outdoors in nature. These professionals study various aspects of the natural world, such as wildlife, ecosystems, geological formations, or plant life, by collecting data and observations directly from the field. Conducting research outdoors allows them to study the environment in its natural state and gain a deeper understanding of the interactions between living organisms and their surroundings.
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Why do some people not like being outdoors in nature?
Some people may not like being outdoors in nature due to a fear of insects or animals, discomfort with unpredictable weather conditions, or a preference for indoor activities. Others may have physical limitations that make it difficult to navigate outdoor terrain or may simply feel more at ease in urban environments. Additionally, some individuals may have had negative past experiences in nature that have influenced their perception of outdoor spaces.
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In which profession do you conduct research outdoors in nature?
I conduct research outdoors in nature as a field biologist. This profession involves studying various aspects of plants, animals, and ecosystems in their natural habitats. Field biologists often spend extended periods of time in the field, collecting data, observing behaviors, and conducting experiments to better understand the natural world. This hands-on approach to research allows for a deeper appreciation and insight into the complexities of the environment.
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Computational Genomics and Structural Bioinformatics in Microbial Science : Microbial Genomics Volume 2
Computational Genomics and Structural Bioinformatics in Microbial Science: Microbial Genomics (Volume 2) covers different aspects of microbial genomics, metagenomics, and functional studies of microbes through informative illustrations of current trends in computational tools and bioinformatics approach in environmental microbiology and clinical diagnosis.This book aims to provide readers with an overview of the microbial genome, computational genomics, and structural bioinformatics in microbial science, as well as the most recent developments in these fields.This book covers a range of topics, including the challenges and opportunities of computational epigenomics, bioinformatics tools for assessing metagenomic data, as well as computed comparative genomics and computational phenotyping of microorganisms relevant to agriculture.Microbial Genomics: Host Adaptation, virulence, and Evolution is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, that are interested in microbial science specifically related to the microbial genome, computing genomics, and bioinformatics.
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Population Genomics with R
Population Genomics With R presents a multidisciplinary approach to the analysis of population genomics.The methods treated cover a large number of topics from traditional population genetics to large-scale genomics with high-throughput sequencing data.Several dozen R packages are examined and integrated to provide a coherent software environment with a wide range of computational, statistical, and graphical tools.Small examples are used to illustrate the basics and published data are used as case studies.Readers are expected to have a basic knowledge of biology, genetics, and statistical inference methods.Graduate students and post-doctorate researchers will find resources to analyze their population genetic and genomic data as well as help them design new studies. The first four chapters review the basics of population genomics, data acquisition, and the use of R to store and manipulate genomic data.Chapter 5 treats the exploration of genomic data, an important issue when analysing large data sets.The other five chapters cover linkage disequilibrium, population genomic structure, geographical structure, past demographic events, and natural selection.These chapters include supervised and unsupervised methods, admixture analysis, an in-depth treatment of multivariate methods, and advice on how to handle GIS data.The analysis of natural selection, a traditional issue in evolutionary biology, has known a revival with modern population genomic data.All chapters include exercises. Supplemental materials are available on-line (http://ape-package.ird.fr/PGR.html).
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Essential Genetics And Genomics
Genetics. Simplified. Dan Hartl once again takes students on the exciting journey of learning about modern genetics in an updated seventh edition of Essential Genetics and Genomics.With carefully chosen topics to help students attain scientific competency, Dr. Hartl expertly covers the fundamentals of genetics from the perspective of genomics, including gene transmission, mutation, expression, and regulation.New and updated Stop & Think problems, Key Concept checks, and Human Connection feature boxes throughout chapters, along with extensive end-of-chapter review and study material that encourages students to analyze and apply new skills, further emphasize the text's focus on student success.The seamless integration of “molecular genetics” and “classical genetics” coupled with the copious practice and problem-solving opportunities make Essential Genetics and Genomics, Seventh Edition a unique resource for learning and applying genetics to our world. To ensure students are prepared for introductory genetics, a new online Readiness Assessment is available to complete prior to diving into the material.Students simply answer the online questions to obtain a personalized score with tailored areas to focus their review.Students are then directed to the color-coded Readiness Review section in the back of the text to practice the areas where study is needed.Sections include Math in Genetics, Science Prerequisites, and Thinking Like a Scientist.Never has learning genetics been so straightforward!
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Bacterial Genetics and Genomics
Understanding of bacterial genetics and genomics is fundamental to understanding bacteria and higher organisms, as well.Novel insights in the fields of genetics and genomics are challenging the once clear borders between the characteristics of bacteria and other life.Biological knowledge of the bacterial world is being viewed under a new light with input from genetic and genomics.Replication of bacterial circular and linear chromosomes, coupled (and uncoupled) transcription and translation, multiprotein systems that enhance survival, wide varieties of ways to control gene and protein expression, and a range of other features all influence the diversity of the microbial world.This text acknowledges that readers have varied knowledge of genetics and microbiology.Therefore, information is presented progressively, to enable all readers to understand the more advanced material in the book. This second edition of Bacterial Genetics and Genomics updates the information from the first edition with advances made over the past five years.This includes descriptions for 10 types of secretion systems, bacteria that can be seen with the naked eye, and differences between coupled transcription-translation and the uncoupled runaway transcription in bacteria.Topic updates include advances in bacteriophage therapy, biotechnology, and understanding bacterial evolution. Key FeaturesGenetics, genomics, and bioinformatics integrated in one placeOver 400 full-colour illustrations explain concepts and mechanisms throughout and are available to instructors for downloadA section dedicated to the application of genetics and genomics techniques, including a chapter devoted to laboratory techniques, which includes useful tips and recommendations for protocols, in addition to troubleshooting and alternative strategiesBulleted key points summarize each chapterExtensive self-study questions related to the chapter text and several discussion topics for study groups to explore furtherThis book is extended and enhanced through a range of digital resources that include:Interactive online quizzes for each chapterFlashcards that allow the reader to test their understanding of key terms from the bookUseful links for online resources associated with Chapters 16 and 17
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Which travel companies are known for fun trips or adventure travel?
Some travel companies known for fun trips or adventure travel include G Adventures, Intrepid Travel, and REI Adventures. These companies offer a wide range of adventurous activities such as hiking, cycling, and wildlife safaris, as well as unique cultural experiences. They cater to travelers looking for immersive and active adventures, and often focus on sustainable and responsible travel practices. Whether it's exploring remote destinations or embarking on adrenaline-pumping activities, these companies are popular choices for those seeking fun and adventure in their travels.
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What professions combine nature and travel?
Professions that combine nature and travel include wildlife photographers, environmental researchers, and park rangers. Wildlife photographers travel to various natural habitats to capture images of animals and landscapes. Environmental researchers often conduct fieldwork in different locations to study ecosystems and wildlife. Park rangers work in national parks and other protected areas, allowing them to be surrounded by nature while also interacting with visitors and helping to preserve the environment.
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What is the name of the adventure nature swimming pool?
The name of the adventure nature swimming pool is "The Grotto."
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How can I teach my daughter to pee outdoors in nature?
To teach your daughter to pee outdoors in nature, you can start by finding a secluded spot where she feels comfortable and safe. Show her how to squat low to the ground and aim away from her body to avoid getting wet. Encourage her to practice in the backyard or on camping trips to build her confidence. It's important to teach her about Leave No Trace principles, such as digging a small hole and covering it up afterwards. Positive reinforcement and patience are key in helping her feel comfortable with this new skill.
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